Clinical Trials at HOAF
At Hematology Oncology Associates of Fredericksburg, we are committed to offering our patients the most advanced comprehensive cancer care. Clinical trials are an integral part of this treatment package, as they offer access to new treatments not yet available outside of the trial. We currently have multiple trials open for enrollment. In addition, we are a research affiliate with VCU Massey Cancer Center in Richmond, Virginia. This affiliation allows our patients to access leading-edge clinical trials while receiving treatment in Fredericksburg.
We encourage you to discuss your options with your provider.
The following studies are open for enrollment:
Protocol I3Y-MC-JPCF: A Randomized, Open-Label, Phase 3 Study of Abemaciclib Combined with Standard Adjuvant Endocrine Therapy versus Standard Adjuvant Endocrine Therapy Alone in Patients with High Risk, Node Positive, Early Stage, Hormone Receptor Positive, Human Epidermal Receptor 2 Negative, Breast Cancer
Objective: To evaluate the efficacy, in terms of IDFS, for patients with HR+, HER2- early stage breast cancer for abemaciclib plus adjuvant endocrine therapy versus adjuvant endocrine therapy alone
A Phase III, Open-Label, Randomized Study to Investigate The Efficacy and Safety of Atezolizumab (Anti−Pd-L1 Antibody) Compared With Best Supportive Care Following Adjuvant Cisplatin-Based Chemotherapy in PD-L1−Selected Patients With Completely Resected Stage IB−IIIA Non−Small Cell Lung Cancer
Objective: To evaluate the efficacy of sixteen cycles of atezolizumab treatment compared with best supportive care as measured by disease-free survival (DFS) as assessed by the investigator
A Randomized Phase III Trial of Bortezomib, LENalidomide and Dexamethasone (VRd) versus Carfilzomib, Lenalidomide, Dexamethasone (CRd) Followed by Limited or Indefinite DURation Lenalidomide MaintenANCE in Patients with Newly Diagnosed Symptomatic Multiple Myeloma (ENDURANCE)
Objective: To compare the overall survival between two strategies of lenalidomide maintenance following induction with a proteasome inhibitor-IMiD combination: limited duration of maintenance (24 months) versus indefinite maintenance therapy until disease progression
Randomized Phase III Trial Evaluating The Role of Weight Loss In Adjuvant Treatment of Overweight And Obese Women With Early Breast Cancer
Objective: To compare the effect of a supervised weight loss intervention plus health education materials versus health education materials alone upon invasive disease free survival in overweight and obese women diagnosed with HER-2 negative, stage II and III breast cancer.
An Open-label Phase 2 Study of Carfilzomib Plus Dexamethasone To Assess Tolerability and Adherence in Subjects With Relapsed or Refractory Multiple Myeloma at US Community Oncology Centers
Objective: Describe tolerability and treatment safety of a Carfilzomib/Dexamethasone (Kd) regimen twice weekly for cycles 1-6 followed by Kd once weekly for cycles 7-12 in subjects with relapsed or refractory multiple myeloma with 1-3 prior lines of therapy at study entry.
A Randomized Phase 3 Study to Evaluate the Efficacy and Safety of Enzastaurin Plus R-CHOP Versus R-CHOP in Treatment-Naïve Subjects with High-Risk Diffuse Large B-Cell Lymphoma Who Possess the Novel Genomic Biomarker DGM1™
Objective: To compare the effect of R-CHOP/plus enzastaurin versus R-CHOP on OS in treatment naïve, high-risk subjects with DLBCL who possess the DGM1™ biomarker.
Learn More About Clinical Trials:
- Clinical Trials
Copyright © 2019 Omni Health Media. All Rights Reserved. […]
- Informed Consent
You may already have experience with signing consent forms for other kinds of medical procedures, such as surgery, or for cancer treatments such as radiation or chemotherapy. However, informed consent for a clinical trial involves much more than just reading and signing a piece of paper. Rather, it involves two essential parts: a document and […]
- The Future of Clinical Trials
Despite the multitude of new oncologic treatment strategies in development and the efforts of the federal government, advocacy organizations, and the biopharmaceutical industry, there has been only modest progress with regard to the time it takes to implement and complete pivotal clinical trials. As patient and physician demand for clinical trials increases over the next […]
- Finding Specific Clinical Trials
Cancer clinical trials are available in many hospitals and clinics throughout the United States. Currently, there are several Internet resources designed to facilitate access and accrual to clinical trials. Unfortunately, no single clinical trials listing service or database contain all the available clinical trials in the United States. One of the more comprehensive sources, however, […]
- The Cost of Clinical Trials
There are two types of costs associated with a trial: Patient care costs; and Research costs Patient care costs: These are costs associated with providing medical goods and services to each patient. Usual care costs include doctor visits, hospital stays, clinical laboratory tests, x-rays, and any other medical costs that occur regardless of whether a […]
Clinical trials are studies that evaluate the effectiveness of new drugs or treatment strategies. The development of more effective cancer treatments requires that new and innovative therapies be evaluated with cancer patients. In oncology, clinical trials are especially important because, in the absence of high cure rates, nearly all therapeutic approaches are developmental in nature. […]
- What Are Clinical Trials?
A clinical trial is a research study designed to evaluate potential new treatment options. These studies are the result of a long and deliberate cancer research process that often takes years. Clinical trials test the safety and effectiveness of new or modified cancer drugs, new drug doses, unique approaches to surgery or radiation therapy, and […]
- Phases of Clinical Trials
Development of new anticancer agents and treatment strategies occurs in four phases. Each phase is designed to determine specific information about the potential new treatment such as its risks, safety and effectiveness compared to standard therapy. The hope is that the new therapy will be an improvement over the previous standard therapy. Phase I Trials: […]
- How are Clinical Trials Conducted?
Clinical trials are designed to test treatments under very specific scientific and ethical guidelines. Clinical trials use written protocols to define the purpose, design and conduct of a specific clinical trial. All of the research centers participating in a particular study use the same research protocol. The protocol is written by the sponsor of the […]
- Participating in Clinical Trials
Clinical trials are designed to evaluate the effectiveness of new treatment interventions. The objective of these clinical trials is to test new therapies in patients who have cancer. Patients participate in clinical trials for several reasons, including: The potential to benefit from a new drug or treatment procedure Improved management of symptoms resulting from treatment […]
- Clinical Trial Safeguards
Both standard care and clinical trials have risks, side effects, and benefits that vary depending on the individual. However, there are rigorous guidelines in place to protect the well-being and safety of clinical trial participants. The physician and research nurse conducting the study will explain any known or anticipated risks ahead of time. Once a […]